Crosslinking Reagents
Medchemexpress LLC DBCO-sulfo-link-biotin | 1363444-70-5 | >95.0% | 653.77 g/mol | C31H35N5O7S2 | 5 MG
DBCO-sulfo-link-biotin is a cleavable linker reagent that combines a dibenzocyclooctyne (DBCO) reactive group with a sulfonated biotin tag for aqueous solubility and affinity capture. It is intended for click chemistry applications such as strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-bearing biomolecules and for use in the synthesis of antibody-drug conjugates. For research use only.
- Enables SPAAC with azide-functionalized biomolecules.
- Contains a sulfonated biotin tag for aqueous solubility and affinity capture.
- Cleavable linker suitable for antibody-drug conjugate synthesis.
- Soluble in DMSO at high concentrations and formulatable for in vivo use.
- Powder stable at -20°C; solutions stable at -80°C for extended storage.
- Available in small milligram quantities for research workflows.
Abcam Traut's reagent, RNA-protein crosslinking (sulfhydryl addition) agent, 1G
MW 137.63 Da, Purity >90%. RNA-protein crosslinking (sulfhydryl addition) agent. Reacts with primary amines. Maintains charge properties similar to the original amino group.
The product is subject to the following: Abcam Restricted Use Statement
Broadpharm Bromoacetamido-PEG23-azide, 1g
Bromoacetamido-PEG23-azide ester is a bifunctional PEG linker with terminal bromoacetamido and azide groups. The bromoacetamido group partakes in nucleophilic substitution, while the azide group undergoes copper-catalyzed click reactions with alkyne, DBCO, BCN. The long PEG chain imparts hydrophilicity. Please contact us for GMP-grade inquiries.
Medchemexpress LLC Octanedioic acid, 1,8-bis(2,5-dioxo-3-sulfo-1-pyrrolidinyl) ester | 82436-77-9 | 98.0% | 528.47 g·mol⁻¹ | C16H20N2O14S2 | 50 MG
BS3 Crosslinker is a water-soluble, non-cleavable homobifunctional crosslinker that reacts with primary amines to form stable amide bonds. It contains sulfo-NHS ester groups that enable efficient conjugation in aqueous buffers, making it suitable for protein crosslinking and antibody-drug conjugate synthesis in research applications.
- Water soluble and membrane impermeable, enabling reactions in aqueous buffers.
- Reacts with primary amines via NHS-ester chemistry for efficient conjugation.
- Forms stable, non-cleavable amide bonds for durable linkages.
- Compatible with antibody-drug conjugate (ADC) and protein crosslinking workflows.
- Supplied with defined purity and characterized molecular weight for reproducibility.
- Available in small lab-friendly pack sizes for research use.
Medchemexpress LLC Trans-sulfo-SMCC | 1286837-77-1 | 90.9% | 414.39 g/mol | C16H18N2O9S | 100 MG
trans-Sulfo-SMCC is a non-cleavable, membrane-permeable crosslinker used for antibody-drug conjugate (ADC) construction and general bioconjugation. It contains maleimide and N-hydroxysuccinimide (NHS) ester functionalities that enable stable conjugation between sulfhydryl and amino groups to form non-cleavable linkages.
- Non-cleavable linker suitable for ADC construction.
- Membrane permeable for potential intracellular delivery.
- Maleimide and NHS-ester reactive groups for thiol-to-amine conjugation.
- Solid, white to off-white, available in multiple quantities including 100 mg.
- Stable as a powder at -20 °C for long-term storage; in solvent stability varies.
Medchemexpress LLC Sulfo-SMCC sodium | 92921-24-9 | 99.9% | 25 MG
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker. It features N-hydroxysuccinimide (NHS) ester and maleimide groups, which react with primary amines and sulfhydryl groups, respectively. This crosslinker has been shown to inhibit the end-to-end annealing of stabilized microtubules.
- Hetero-bifunctional, noncleavable ADC crosslinker
- Contains N-hydroxysuccinimide (NHS) ester and maleimide groups
- Reacts with primary amines and sulfhydryl groups
Thermo Scientific™ SBAP (succinimidyl 3-(bromoacetamido)propionate)
Crosslink amines to sulfhydryls with this short crosslinker composed of NHS-ester and bromoacetyl (haloacetyl) groups at ends of a 7-atom (6.2A) spacer arm.
Med Vet International Comfor-Trate (Maropitant Citrate) Antiemetic Tablets For Dogs, 16mg, 4 Count
Comfor-trate (maropitant citrate) Tablets are indicated for the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs.
![eMolecules Sulfo-SMCC | Combi-Blocks | 92921-24-9 | MFCD00054978 | 436.370 | C16H17N2NaO9S | 95.000 | [Na+].[O-]S(=O)(=O)C1CC(=O)N(OC(=O)C2CCC(CN3C(=O)C=CC3=O)CC2)C1=O | 1g | 457919453](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC2103228.JPG-250.jpg)
eMolecules Sulfo-SMCC | Combi-Blocks | 92921-24-9 | MFCD00054978 | 436.370 | C16H17N2NaO9S | 95.000 | [Na+].[O-]S(=O)(=O)C1CC(=O)N(OC(=O)C2CCC(CN3C(=O)C=CC3=O)CC2)C1=O | 1g | 457919453
Sulfo-SMCC | Combi-Blocks | 92921-24-9 | MFCD00054978 | 436.370 | C16H17N2NaO9S | 95.000 | [Na+].[O-]S(=O)(=O)C1CC(=O)N(OC(=O)C2CCC(CN3C(=O)C=CC3=O)CC2)C1=O | 1g | 457919453